Chemicals are pure substances and mixtures composed of various elements, whether natural or man-made. As many as 7 million chemicals exist worldwide. Each year, more than 1000 new chemicals appear worldwide.
Chemicals' potential for harming human health and polluting the environment is growing in importance as their types and quantities expand year after year. Toxicological evaluation of chemicals is a prerequisite for safe chemical management.
- To provide research on chemical safety evaluation systems based on risk levels.
- To provide safety evaluation based on in vitro human cytotoxicity test, in vitro metabolic stability test, in vitro animal or human liver microsomal inhibition test, in vitro animal or human primary hepatocyte induction test, animal level toxicokinetic test, etc.
- To provide safety evaluation based on computational toxicology models.
- To provide a multi-omics-based evaluation of adverse drug reactions, drug interactions, time-toxicity effect relationship, dose-toxicity effect relationship, and other toxicity mechanisms.
- To provide research on the physicochemical properties and chemical structures of the main components, efficacy components/marker components of special food subjects.
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Toxicological studies of chemicals play an important role in ensuring the safety of chemical product.
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Mutagenicity evaluation of chemicals is of great importance for the prevention of human diseases and the control of environmental pollution. Mutagenicity testing refers to the primary screening of carcinogens and is an important tool for cancer prevention in humans.