Over the course of the last couple years, the Chicago White Sox have established themselves as serious contenders in the American League and on Friday night they'll have a chance to showcase that to a national audience as they take on the Tampa Bay Rays. However, Chicago has dealt with some injury woes early in the 2022 MLB season,Las Vegas Raiders Jerseys losing starting pitchers Lance Lynn and Lucas Giolito as well as key position players Yoan Moncada and A.J. Pollock. But there's still a strong core in place and MLB daily Fantasy players have done well by stacking players like Tim Anderson, Luis Robert and Andrew Vaughn so far this year.

The White Sox will throw out Dylan Cease as their starter on Friday while the Rays will send Drew Rasmussen. So should you be loading White Sox sluggers into your MLB DFS lineups or are there better options in the MLB DFS player pool for Friday night? Before you make your MLB DFS picks, be sure to check out the MLB DFS advice, strategy and projections from SportsLine daily Fantasy expert Mike McClure.

McClure is a daily Fantasy pro who has won almost $2 million in his career. And when it comes to daily Fantasy baseball, McClure is at his best. Recognized in the book "Fantasy Football (and Baseball) for Smart People: How to Turn Your Hobby into a Fortune" Boston Red Sox Jerseys as a top MLB DFS player, McClure's proprietary projection model simulates each game 10,000 times, taking factors such as matchups and recent results into account. This allows him to find the best values on every site.

On Thursday, McClure highlighted Padres starting pitcher Joe Musgrove in his MLB DFS player pool on both FanDuel and DraftKings. The result: Musgrove threw 6.2 innings of shutout ball, giving up four hits and striking out six on his way to a win to return 28.6 points on DraftKings and 48 points on FanDuel. Anybody that included him in their lineups was well on the way to a profitable day.Now, with the 2022 MLB season in full swing, McClure has locked in his top MLB daily Fantasy picks for Friday, April 15. Head to SportsLine now to see them. 

McClure's top MLB DFS picks for April 15, 2022
One of McClure's top MLB DFS picks for Friday is Dodgers first baseman Freddie Freeman, who is listed at $5,100 on DraftKings and $3,600 on FanDuel. The 2020 NL MVP and five-time All-Star joined the Dodgers in free agency after 12 years in Atlanta. He signed a six-year, $162 million contract shortly after the MLB lockout ended and he seems to be finding his rhythm in Dodger Blue the last few games.

Freeman is 7-for-19 during a current four-game hitting streak and he's had multi-hit efforts in each of his last three games. He's also had an extra-base hit in each of those three games and he should enjoy the matchup against Reds right-hander Vladimir Gutierrez on Friday. Freeman is 2-for-6 with a couple of doubles and an RBI off Gutierrez and has a career OPS of .941 off right-handed pitching.

Another part of McClure's optimal MLB DFS strategy includes rostering Rangers second baseman Marcus Semien ($5,000 on DraftKings and $3,300 on FanDuel). After emerging as a star late Boston Red Sox Jersey in his career with the Athletics and then taking a one-year, prove-it deal with the Blue Jays to enhance his value last season, Semien was given a seven-year, $175 million contract to join the Rangers this offseason.

Now he pairs up the middle with former Dodgers shortstop Corey Seager, who the Rangers spent an additional $325 million on. And while Semien is off to a slow start (3-for-27), his combination of speed, power and plate discipline is bound to pay off. Last season, Semien had 45 home runs, 102 RBIs and 15 stolen bases on his way to a third-place finish in the AL MVP voting for the second time in three years. 

How to set your MLB DFS lineups for April 15, 2022 
McClure is also targeting an undervalued player who is set to explode for huge numbers on Friday. The stars are aligning for him to return tournament-winning value and he comes at a price that won't break the bank. You can only see who it is here.