D2r 2.4 Release Date & the Time Diablo 2 Resurrected Somehow, Blizzard has changed up Plague's stats. Plague's preferred order has changed to Cham + Shael + Um. It's with a substantial cost, but also a new purpose for D2R Items the under-used Cham rune. The Plague that's been updated Plague reads like some strange experimental build that has a very specific use case. Everyone is trying to figure out why you should choose Plague over something...